CD1b antibody (AA 18-303)

Catalog No. ABIN5611269

Product Details anti-CD1b Antibody

Target: CD1b (CD1B)

Binding Specificity: AA 18-303

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1b antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Purpose: CD1B Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD1B (AA: 18-303) expressed in E. Coli.

Clone: 1D6B7

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD1b

Target: CD1b (CD1B)

Alternative Name: CD1B (CD1B Products)

Background:

Description: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Aliases: R1, CD1, CD1A

Molecular Weight: 37kDa

Gene ID: 910

HGNC: 910

UniProt: P29016