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CCR3 antibody

CCR3 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 8E9H10 unconjugated
Catalog No. ABIN5611257
  • Target See all CCR3 Antibodies
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    Reactivity
    • 79
    • 30
    • 24
    • 4
    Human
    Host
    • 59
    • 14
    • 5
    • 4
    Mouse
    Clonality
    • 62
    • 19
    • 1
    Monoclonal
    Conjugate
    • 38
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR3 antibody is un-conjugated
    Application
    • 47
    • 26
    • 24
    • 17
    • 14
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Purpose
    CD193 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD193 (AA: mix) expressed in E. Coli.
    Clone
    8E9H10
    Isotype
    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    Alternative Name
    CD193 (CCR3 Products)
    Synonyms
    CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
    Background

    Description: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

    Aliases: CKR3, CCR3, CMKBR3, CC-CKR-3

    Molecular Weight
    41kDa
    Gene ID
    1232
    HGNC
    1232
    UniProt
    P51677
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