CCR3 antibody
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- Target See all CCR3 Antibodies
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CCR3 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CD193 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD193 (AA: mix) expressed in E. Coli.
- Clone
- 8E9H10
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Alternative Name
- CD193 (CCR3 Products)
- Synonyms
- CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
- Background
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Description: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
Aliases: CKR3, CCR3, CMKBR3, CC-CKR-3
- Molecular Weight
- 41kDa
- Gene ID
- 1232
- HGNC
- 1232
- UniProt
- P51677
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