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BCL6 antibody (AA 147-276)

BCL6 Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 2G1B6 unconjugated
Catalog No. ABIN5611253
  • Target See all BCL6 Antibodies
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    Binding Specificity
    • 28
    • 22
    • 11
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-276
    Reactivity
    • 127
    • 58
    • 26
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 75
    • 52
    • 1
    Mouse
    Clonality
    • 65
    • 63
    Monoclonal
    Conjugate
    • 68
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    This BCL6 antibody is un-conjugated
    Application
    • 75
    • 46
    • 36
    • 33
    • 32
    • 15
    • 14
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purpose
    BCL6 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
    Clone
    2G1B6
    Isotype
    IgG1
    Top Product
    Discover our top product BCL6 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    Alternative Name
    BCL6 (BCL6 Products)
    Synonyms
    bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
    Background

    Description: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

    Aliases: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27

    Molecular Weight
    78.8kDa
    Gene ID
    604
    HGNC
    604
    UniProt
    P41182
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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