BCL6 antibody (AA 147-276)
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- Target See all BCL6 Antibodies
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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Binding Specificity
- AA 147-276
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BCL6 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purpose
- BCL6 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
- Clone
- 2G1B6
- Isotype
- IgG1
- Top Product
- Discover our top product BCL6 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- Alternative Name
- BCL6 (BCL6 Products)
- Synonyms
- bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
- Background
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Description: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Aliases: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27
- Molecular Weight
- 78.8kDa
- Gene ID
- 604
- HGNC
- 604
- UniProt
- P41182
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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