RUNX1 antibody (AA 237-337)

Catalog No. ABIN5611238

Product Details anti-RUNX1 Antibody

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Binding Specificity: AA 237-337

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: RUNX1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RUNX1 (AA: 237-337) expressed in E. Coli.

Clone: 6C12A5

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Alternative Name: RUNX1 (RUNX1 Products)

Background:

Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Aliases: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha

Molecular Weight: 48.7kDa

Gene ID: 861

HGNC: 861

UniProt: Q01196