ARFGAP1 antibody (AA 270-414)

Catalog No. ABIN5611220

Product Details anti-ARFGAP1 Antibody

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Binding Specificity: AA 270-414

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ARFGAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human ARFGAP1 (AA: 270-414) expressed in E. coli.

Clone: 1C4E2

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Alternative Name: ARFGAP1 (ARFGAP1 Products)

Synonyms: ARF1GAP antibody, HRIHFB2281 antibody, AI115377 antibody, Arf1gap antibody, Arf GAP1 antibody, arf1gap antibody, atfb1 antibody, atfb3 antibody, jlns1 antibody, k(v)7.1 antibody, kcna8 antibody, kcna9 antibody, kv1.9 antibody, kv7.1 antibody, kvlqt1 antibody, lqt antibody, lqt1 antibody, rws antibody, sqt2 antibody, wrs antibody, ARFGAP3 antibody, ADP ribosylation factor GTPase activating protein 1 antibody, ADP-ribosylation factor GTPase activating protein 1 antibody, ADP ribosylation factor GTPase activating protein 1 S homeolog antibody, putative ADP-ribosylation factor GTPase activating protein 1 antibody, ATP-dependent RNA helicase DBP9 antibody, ARFGAP1 antibody, Arfgap1 antibody, arfgap1.S antibody, Tb11.01.6060 antibody, arfgap1 antibody, LMJF_32_1230 antibody, MGYG_02419 antibody

Background:

Description: The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

Aliases: ARF1GAP, HRIHFB2281

Molecular Weight: 44.7 kDa

Gene ID: 55738

HGNC: 55738

Pathways: p53 Signaling, ER-Nucleus Signaling, Unfolded Protein Response