NLRC4 antibody (pSer533)

Catalog No. ABIN5611209

Product Details anti-NLRC4 Antibody

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Binding Specificity: pSer533

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This NLRC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purpose: Phospho-NLRC4 (Ser-533) Antibody

Purification: Purified antibody

Immunogen: Synthesized peptide of mouse phospho-NLRC4(Ser-533) (AA: 525-538) expressed in E. Coli.

Clone: 4B7B7

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Alternative Name: NLRC4 (NLRC4 Products)

Background:

Description: NLRC4 is a cytosolic NOD (nucleotide binding and oligomerization domain)-like receptor (NLR) that can trigger inflammasome formation in response to bacterial flagellin, an immunodominant antigen in the intestine.

Aliases: CLAN, IPAF, CLAN1, CLANA, CLANB, CLANC, CLAND, Card12, 9530011P19Rik

Molecular Weight: 116.7kDa

Gene ID: 268973

HGNC: 268973

UniProt: Q3UP24

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome