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Metabotropic Glutamate Receptor 6 antibody (AA 480-585)

GRM6 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 7D9C9 unconjugated
Catalog No. ABIN5611180
  • Target See all Metabotropic Glutamate Receptor 6 (GRM6) Antibodies
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    Binding Specificity
    • 12
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 480-585
    Reactivity
    • 35
    • 12
    • 11
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 2
    Mouse
    Clonality
    • 36
    • 1
    Monoclonal
    Conjugate
    • 28
    • 3
    • 2
    • 2
    • 1
    • 1
    This Metabotropic Glutamate Receptor 6 antibody is un-conjugated
    Application
    • 31
    • 17
    • 11
    • 5
    • 5
    • 3
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Purpose
    GRM6 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human GRM6 (AA: 480-585) expressed in E. Coli.
    Clone
    7D9C9
    Isotype
    IgG1
    Top Product
    Discover our top product GRM6 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    Alternative Name
    GRM6 (GRM6 Products)
    Background

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    Aliases: mGlu6, CSNB1B, GPRC1F, MGLUR6

    Molecular Weight
    95.5kDa
    Gene ID
    2916
    HGNC
    2916
    UniProt
    O15303
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