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Metabotropic Glutamate Receptor 3 antibody (AA 433-576)

GRM3 Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 6H10C3 unconjugated
Catalog No. ABIN5611176
  • Target See all Metabotropic Glutamate Receptor 3 (GRM3) Antibodies
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Binding Specificity
    • 16
    • 9
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 433-576
    Reactivity
    • 36
    • 29
    • 12
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 51
    • 1
    • 1
    Mouse
    Clonality
    • 51
    • 2
    Monoclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 3 antibody is un-conjugated
    Application
    • 41
    • 18
    • 15
    • 9
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. coli.
    Clone
    6H10C3
    Isotype
    IgG1
    Top Product
    Discover our top product GRM3 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Alternative Name
    GRM3 (GRM3 Products)
    Synonyms
    GLUR3 antibody, GPRC1C antibody, MGLUR3 antibody, mGlu3 antibody, 0710001G23Rik antibody, Gprc1c antibody, mGluR3 antibody, glutamate metabotropic receptor 3 antibody, glutamate receptor, metabotropic 3 antibody, GRM3 antibody, Grm3 antibody
    Background

    Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3

    Molecular Weight
    99 kDa
    Gene ID
    2913
    HGNC
    2913
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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