IL9 Receptor antibody (AA 41-270)

Catalog No. ABIN5611173

Product Details anti-IL9 Receptor Antibody

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Binding Specificity: AA 41-270

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL9 Receptor antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Neutralization (Neut), Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human CD129 (AA: extra 41-270) expressed in E. coli.

Clone: 1C2A6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Alternative Name: CD129 (IL9R Products)

Synonyms: CD129 antibody, IL-9R antibody, interleukin 9 receptor antibody, IL9R antibody, Il9r antibody

Background:

Description: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Aliases: IL9R, IL-9R

Molecular Weight: 57.1 kDa

Gene ID: 3581

HGNC: 3581

Pathways: JAK-STAT Signaling, Growth Factor Binding