GRM7 antibody (AA 454-590)
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- Target See all GRM7 Antibodies
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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Binding Specificity
- AA 454-590
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GRM7 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- GRM7 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human GRM7 (AA: 454-590) expressed in E. Coli.
- Clone
- 7G8A2
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
- Alternative Name
- GRM7 (GRM7 Products)
- Synonyms
- MGLUR7 antibody, GLUR7 antibody, GPRC1G antibody, MGLU7 antibody, 6330570A01Rik antibody, BB176677 antibody, C030018L03 antibody, E130018M02Rik antibody, Gpr1g antibody, Gprc1g antibody, mGluR7 antibody, glutamate metabotropic receptor 7 antibody, glutamate receptor, metabotropic 7 antibody, GRM7 antibody, Grm7 antibody
- Background
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: GLUR7, MGLU7, GPRC1G, MGLUR7, PPP1R87
- Molecular Weight
- 102.3kDa
- Gene ID
- 2917
- HGNC
- 2917
- UniProt
- Q14831
- Pathways
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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