GRIK3 antibody (AA 32-173)

Catalog No. ABIN5611156

Product Details anti-GRIK3 Antibody

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Binding Specificity: AA 32-173

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIK3 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Purpose: GRIK3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GRIK3 (AA: 32-173) expressed in E. Coli.

Clone: 2B3D1

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for GRIK3

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Alternative Name: GRIK3 (GRIK3 Products)

Synonyms: GRIK3 antibody, eaa5 antibody, glr7 antibody, glur7 antibody, 9630027E11 antibody, GluK3 antibody, GluR7-3 antibody, Glur-7 antibody, Glur7 antibody, GluR7 antibody, gluR-7 antibody, EAA5 antibody, GLR7 antibody, GLUR7 antibody, GluR7a antibody, glutamate ionotropic receptor kainate type subunit 3 antibody, glutamate receptor, ionotropic, kainate 3 L homeolog antibody, glutamate receptor, ionotropic, kainate 3 antibody, GRIK3 antibody, grik3.L antibody, Grik3 antibody

Background:

Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Aliases: EAA5, GLR7, GLUR7, GluK3, GluR7a

Molecular Weight: 104kDa

Gene ID: 2899

HGNC: 2899

Pathways: Synaptic Membrane