GRK6 antibody (AA 71-170)
GRK6
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
8D4
unconjugated
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Target
See all GRK6 Antibodies
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GRK6
(G Protein-Coupled Receptor Kinase 6 (GRK6))
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Binding Specificity
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AA 71-170
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Reactivity
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Human
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Host
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Mouse
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Clonality
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Monoclonal
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Conjugate
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This GRK6 antibody is un-conjugated
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Application
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Western Blotting (WB), ELISA
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Purpose
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Mouse monoclonal antibody raised against a partial recombinant GRK6.
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Sequence
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CATRPELSRC VAFLDGVAEY EVTPDDKRKA CGRQLTQNFL SHTGPDLIPE VPRQLVTNCT QRLEQGPCKD LFQELTRLTH EYLSVAPFAD YLDSIYFNRF
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Cross-Reactivity
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Human
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Characteristics
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Antibody Reactive Against Recombinant Protein.
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Immunogen
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GRK6 (AAH17272, 71 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone
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8D4
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Isotype
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IgG2b
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Top Product
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Discover our top product GRK6 Primary Antibody
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Buffer
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In 1x PBS, pH 7.4
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Handling Advice
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Aliquot to avoid repeated freezing and thawing.
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Storage
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-20 °C
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Storage Comment
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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McCormick, Segarra, Gasperini, Gulino, Tosato: "Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor." in: PLoS ONE, Vol. 4, Issue 12, pp. e8102, (2009) (PubMed).
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Target
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GRK6
(G Protein-Coupled Receptor Kinase 6 (GRK6))
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Alternative Name
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GRK6 (GRK6 Products)
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Synonyms
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MGC83187 antibody, GRK6 antibody, GPRK6 antibody, Gprk6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase 6 S homeolog antibody, GRK6 antibody, grk6.S antibody, grk6 antibody, Grk6 antibody
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Background
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Full Gene Name: G protein-coupled receptor kinase 6
Synonyms: FLJ32135,GPRK6
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Gene ID
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2870
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Pathways
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Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity
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