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PD-1 antibody (AA 21-170)

PDCD1 Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 3E12A10 unconjugated
Catalog No. ABIN5611149
  • Target See all PD-1 (PDCD1) Antibodies
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Binding Specificity
    • 16
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-170
    Reactivity
    • 144
    • 77
    • 25
    • 5
    • 3
    • 1
    Human
    Host
    • 82
    • 64
    • 25
    • 13
    • 11
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 135
    • 62
    • 2
    Monoclonal
    Conjugate
    • 94
    • 15
    • 13
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PD-1 antibody is un-conjugated
    Application
    • 129
    • 58
    • 43
    • 38
    • 35
    • 19
    • 13
    • 13
    • 13
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Purpose
    PD1 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PD1 (AA: 21-170) expressed in HEK293 cells.
    Clone
    3E12A10
    Isotype
    IgG2a
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Alternative Name
    PD1 (PDCD1 Products)
    Synonyms
    CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
    Background

    Description: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

    Aliases: PDCD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1

    Molecular Weight
    31.6KD
    Gene ID
    5133
    HGNC
    5133
    UniProt
    Q15116
    Pathways
    Cancer Immune Checkpoints
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