PD-1 antibody (AA 21-170)
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- Target See all PD-1 (PDCD1) Antibodies
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Binding Specificity
- AA 21-170
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PD-1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
- Purpose
- PD1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PD1 (AA: 21-170) expressed in HEK293 cells.
- Clone
- 3E12A10
- Isotype
- IgG2a
- Top Product
- Discover our top product PDCD1 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Alternative Name
- PD1 (PDCD1 Products)
- Synonyms
- CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
- Background
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Description: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Aliases: PDCD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1
- Molecular Weight
- 31.6KD
- Gene ID
- 5133
- HGNC
- 5133
- UniProt
- Q15116
- Pathways
- Cancer Immune Checkpoints
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