Integrin beta 4 antibody (AA 29-206)
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- Target See all Integrin beta 4 (ITGB4) Antibodies
- Integrin beta 4 (ITGB4)
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Binding Specificity
- AA 29-206
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin beta 4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
- Purpose
- CD104 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD104 (AA: 29-206) expressed in E. Coli.
- Clone
- 5G3G5
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGB4 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Integrin beta 4 (ITGB4)
- Alternative Name
- CD104 (ITGB4 Products)
- Synonyms
- AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
- Background
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Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Aliases: ITGB4, GP150
- Molecular Weight
- 202.2kDa
- Gene ID
- 3691
- HGNC
- 3691
- UniProt
- P16144
- Pathways
- Integrin Complex
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