Aurora A antibody (AA 268-404)

Catalog No. ABIN5611122

Product Details anti-Aurora A Antibody

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Binding Specificity: AA 268-404

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purpose: AURKA Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human AURKA (AA: 268-404) expressed in E. Coli.

Clone: 4H5A8

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: AURKA (AURKA Products)

Background:

Description: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Aliases: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47

Molecular Weight: 45.8kDa

Gene ID: 6790

HGNC: 6790

UniProt: O14965

Pathways: Cell Division Cycle, Asymmetric Protein Localization