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eIF4EBP1 antibody (pSer65)

EIF4EBP1 Reactivity: Human IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 1E2E7 unconjugated
Catalog No. ABIN5611114
  • Target See all eIF4EBP1 (EIF4EBP1) Antibodies
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Binding Specificity
    • 25
    • 20
    • 20
    • 18
    • 16
    • 15
    • 10
    • 10
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer65
    Reactivity
    • 208
    • 155
    • 110
    • 21
    • 14
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 225
    • 12
    • 4
    Mouse
    Clonality
    • 213
    • 30
    Monoclonal
    Conjugate
    • 103
    • 22
    • 17
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This eIF4EBP1 antibody is un-conjugated
    Application
    • 198
    • 82
    • 75
    • 67
    • 66
    • 43
    • 22
    • 21
    • 16
    • 10
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purpose
    Phospho-4E-BP1 (Ser65) Antibody
    Purification
    Purified antibody
    Immunogen
    Synthesized peptide of human Phospho-4E-BP1 (Ser65).
    Clone
    1E2E7
    Isotype
    IgG1
    Top Product
    Discover our top product EIF4EBP1 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Alternative Name
    4E-BP1 (EIF4EBP1 Products)
    Background

    Description: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

    Aliases: EIF4EBP1, BP-1, 4EBP1, 4E-BP1, PHAS-I

    Molecular Weight
    12.6kDa
    Gene ID
    1978
    HGNC
    1978
    UniProt
    Q13541
    Pathways
    MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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