GABBR1 antibody (AA 52-151)

Catalog No. ABIN560976

Product Details anti-GABBR1 Antibody

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Binding Specificity: AA 52-151

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GABBR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant GABBR1.

Sequence: AVYIGALFPM SGGWPGGQAC QPAVEMALED VNSRRDILPD YELKLIHHDS KCDPGQATKY LYELLYNDPI KIILMPGCSS VSTLVAEAAR MWNLIVLSYG

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GABBR1 (AAH50532, 52 a.a. ~ 151 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2D7

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GABBR1 antibody (ABIN560976)

Dogan Onugoren, Deuretzbacher, Haensch, Hagedorn, Halve, Isenmann, Kramme, Lohner, Melzer, Monotti, Presslauer, Schäbitz, Steffanoni, Stoeck, Strittmatter, Stögbauer, Trinka, von Oertzen, Wiendl et al.: "Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series. ..." in: Journal of neurology, neurosurgery, and psychiatry, (2014) (PubMed).

Dogan Onugoren, Rauschka, Bien: "Conjoint occurrence of GABAB receptor antibodies in Lambert-Eaton myasthenic syndrome with antibodies to the voltage gated calcium channel." in: Journal of neuroimmunology, Vol. 273, Issue 1-2, pp. 115-6, (2014) (PubMed).

Wang, Chen, Chen, Wolpaw, Chen: "Cortical stimulation causes long-term changes in H-reflexes and spinal motoneuron GABA receptors." in: Journal of neurophysiology, Vol. 108, Issue 10, pp. 2668-78, (2012) (PubMed).

Tse, Su, Chang, Tsang, Yu, Tang, See, Hsueh, Yang, Hao, Li, Wang, Liao, Chen, Lin, Jorgensen, Chang, Shugart: "Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3." in: American journal of human genetics, Vol. 85, Issue 2, pp. 194-203, (2009) (PubMed).

Target Details for GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Alternative Name: GABBR1 (GABBR1 Products)

Synonyms: GABABR1 antibody, GABBR1-3 antibody, GB1 antibody, GPRC3A antibody, dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, gabbr1 antibody, GABBR1 antibody, GABA(B)R1 antibody, GABAB1 antibody, GABAbR1 antibody, bM573K1.1 antibody, gamma-aminobutyric acid type B receptor subunit 1 antibody, gamma-aminobutyric acid (GABA) B receptor, 1a antibody, gamma-aminobutyric acid (GABA) B receptor, 1 antibody, GABBR1 antibody, gabbr1a antibody, gabbr1 antibody, Gabbr1 antibody

Background: Full Gene Name: gamma-aminobutyric acid (GABA) B receptor, 1
Synonyms: FLJ92613,GABAB(1e),GABABR1,GABBR1-3,GPRC3A,dJ271M21.1.1,dJ271M21.1.2,hGB1a

Gene ID: 2550

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process