ETV5 antibody (AA 181-290)

Catalog No. ABIN560808

Product Details anti-ETV5 Antibody

Target: ETV5 (Ets Variant 5 (ETV5))

Binding Specificity: AA 181-290

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETV5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant ETV5.

Sequence: LPEPGPQQQT FAVPRPPHQP LQMPKMMPEN QYPSEQRFQR QLSEPCHPFP PQPGVPGDNR PSYHRQMSEP IVPAAPPPPQ GFKQEYHDPL YEHGVPGMPG PPAHGFQSPM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ETV5 (NP_004445, 181 a.a. ~ 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 7C10

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ETV5 antibody (ABIN560808)

Lu, Zhang, Huang, Song, Tomaino, Ehrenberger, Lim, Liu, Bronson, Bowden, Brock, Krop, Dillon, Gygi, Mills, Richardson, Signoretti, Yaffe, Kaelin: "Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor." in: Cancer cell, Vol. 26, Issue 2, pp. 222-34, (2014) (PubMed).

Yang, Chen, Li, Lynch, Brisken, Schmidt: "Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression." in: Molecular and cellular biology, Vol. 30, Issue 12, pp. 3111-25, (2010) (PubMed).

Helgeson, Tomlins, Shah, Laxman, Cao, Prensner, Cao, Singla, Montie, Varambally, Mehra, Chinnaiyan: "Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer." in: Cancer research, Vol. 68, Issue 1, pp. 73-80, (2008) (PubMed).

Target Details for ETV5

Target: ETV5 (Ets Variant 5 (ETV5))

Alternative Name: ETV5 (ETV5 Products)

Synonyms: ERM antibody, etv5 antibody, fj87h10 antibody, id:ibd5133 antibody, wu:fj87h10 antibody, zgc:55647 antibody, 1110005E01Rik antibody, 8430401F14Rik antibody, ETS variant 5 antibody, ets variant 5 antibody, ets variant 5a antibody, ETV5 antibody, Etv5 antibody, etv5a antibody

Background: Full Gene Name: ets variant 5
Synonyms: ERM

Gene ID: 2119

NCBI Accession: NM_004454

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development