EPH Receptor B3 antibody (AA 899-997)

Catalog No. ABIN560764

Product Details anti-EPH Receptor B3 Antibody

Target: EPH Receptor B3 (EPHB3)

Binding Specificity: AA 899-997

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant EPHB3.

Sequence: AASLKVIASA QSGMSQPLLD RTVPDYTTFT TVGDWLDAIK MGRYKESFVS AGFASFDLVA QMTAEDLLRI GVTLAGHQKK ILSSIQDMRL QMNQTLPVQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: EPHB3 (NP_004434, 899 a.a. ~ 997 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1B3

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-EPH Receptor B3 antibody (ABIN560764)

Schauer, Stoecklein, Theisen, Kröpil, Baldus, Hoelscher, Feith, Bölke, Matuschek, Budach, Knoefel: "The simultaneous expression of both ephrin B3 receptor and E-cadherin in Barrett`s adenocarcinoma is associated with favorable clinical staging." in: European journal of medical research, Vol. 17, pp. 10, (2012) (PubMed).

Rönsch, Jäger, Schöpflin, Danciu, Lassmann, Hecht: "Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer." in: Epigenetics : official journal of the DNA Methylation Society, Vol. 6, Issue 5, pp. 610-22, (2011) (PubMed).

Ishii, Nakajima, Ogawa: "Complementary expression of EphB receptors and ephrin-B ligand in the pyloric and duodenal epithelium of adult mice." in: Histochemistry and cell biology, Vol. 136, Issue 3, pp. 345-56, (2011) (PubMed).

Ogawa, Takemoto, Ishii, Pasquale, Nakajima: "Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium." in: Histochemistry and cell biology, Vol. 136, Issue 6, pp. 617-36, (2011) (PubMed).

Schauer, Janssen, Rimkus, Raggi, Feith, Friess, Theisen: "Microarray-based response prediction in esophageal adenocarcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 1, pp. 330-7, (2010) (PubMed).

Target Details for EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Alternative Name: EPHB3 (EPHB3 Products)

Synonyms: tck antibody, MGC83457 antibody, EPHB3 antibody, ETK2 antibody, HEK2 antibody, TYRO6 antibody, AW456895 antibody, Cek10 antibody, Etk2 antibody, MDK5 antibody, Sek4 antibody, Tyro6 antibody, CEK10 antibody, EK10 antibody, ek3 antibody, ephb3 antibody, fc62d03 antibody, rtk3 antibody, wu:fc62d03 antibody, zek3 antibody, EPH receptor B3 antibody, EPH receptor B3 L homeolog antibody, Eph receptor B3 antibody, eph receptor B3a antibody, Eph receptor tyrosine kinase antibody, EPHB3 antibody, ephb3.L antibody, ephb3 antibody, Ephb3 antibody, ephb3a antibody

Background: Full Gene Name: EPH receptor B3
Synonyms: ETK2,HEK2,TYRO6

Gene ID: 2049

NCBI Accession: NM_004443

Pathways: RTK Signaling