EPH Receptor B3 antibody (AA 899-997)

Catalog No. ABIN560764

Product Details anti-EPH Receptor B3 Antibody

Target: EPH Receptor B3 (EPHB3)

Binding Specificity: AA 899-997

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant EPHB3.

Sequence: AASLKVIASA QSGMSQPLLD RTVPDYTTFT TVGDWLDAIK MGRYKESFVS AGFASFDLVA QMTAEDLLRI GVTLAGHQKK ILSSIQDMRL QMNQTLPVQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: EPHB3 (NP_004434, 899 a.a. ~ 997 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1B3

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-EPH Receptor B3 antibody (ABIN560764)

Schauer, Stoecklein, Theisen, Kröpil, Baldus, Hoelscher, Feith, Bölke, Matuschek, Budach, Knoefel: "The simultaneous expression of both ephrin B3 receptor and E-cadherin in Barrett`s adenocarcinoma is associated with favorable clinical staging." in: European journal of medical research, Vol. 17, pp. 10, (2012) (PubMed).

Rönsch, Jäger, Schöpflin, Danciu, Lassmann, Hecht: "Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer." in: Epigenetics : official journal of the DNA Methylation Society, Vol. 6, Issue 5, pp. 610-22, (2011) (PubMed).

Ishii, Nakajima, Ogawa: "Complementary expression of EphB receptors and ephrin-B ligand in the pyloric and duodenal epithelium of adult mice." in: Histochemistry and cell biology, Vol. 136, Issue 3, pp. 345-56, (2011) (PubMed).

Ogawa, Takemoto, Ishii, Pasquale, Nakajima: "Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium." in: Histochemistry and cell biology, Vol. 136, Issue 6, pp. 617-36, (2011) (PubMed).

Schauer, Janssen, Rimkus, Raggi, Feith, Friess, Theisen: "Microarray-based response prediction in esophageal adenocarcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 1, pp. 330-7, (2010) (PubMed).

Target Details for EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Alternative Name: EPHB3 (EPHB3 Products)

Background: Full Gene Name: EPH receptor B3
Synonyms: ETK2,HEK2,TYRO6

Gene ID: 2049

NCBI Accession: NM_004443

Pathways: RTK Signaling