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EPH Receptor B3 antibody (AA 899-997)

EPHB3 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1B3 unconjugated
Catalog No. ABIN560764
  • Target See all EPH Receptor B3 (EPHB3) Antibodies
    EPH Receptor B3 (EPHB3)
    Binding Specificity
    • 15
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 899-997
    Reactivity
    • 72
    • 28
    • 16
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 64
    • 9
    • 1
    Mouse
    Clonality
    • 66
    • 8
    Monoclonal
    Conjugate
    • 39
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPH Receptor B3 antibody is un-conjugated
    Application
    • 58
    • 29
    • 17
    • 14
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant EPHB3.
    Sequence
    AASLKVIASA QSGMSQPLLD RTVPDYTTFT TVGDWLDAIK MGRYKESFVS AGFASFDLVA QMTAEDLLRI GVTLAGHQKK ILSSIQDMRL QMNQTLPVQ
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    EPHB3 (NP_004434, 899 a.a. ~ 997 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1B3
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Schauer, Stoecklein, Theisen, Kröpil, Baldus, Hoelscher, Feith, Bölke, Matuschek, Budach, Knoefel: "The simultaneous expression of both ephrin B3 receptor and E-cadherin in Barrett`s adenocarcinoma is associated with favorable clinical staging." in: European journal of medical research, Vol. 17, pp. 10, (2012) (PubMed).

    Rönsch, Jäger, Schöpflin, Danciu, Lassmann, Hecht: "Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer." in: Epigenetics : official journal of the DNA Methylation Society, Vol. 6, Issue 5, pp. 610-22, (2011) (PubMed).

    Ishii, Nakajima, Ogawa: "Complementary expression of EphB receptors and ephrin-B ligand in the pyloric and duodenal epithelium of adult mice." in: Histochemistry and cell biology, Vol. 136, Issue 3, pp. 345-56, (2011) (PubMed).

    Ogawa, Takemoto, Ishii, Pasquale, Nakajima: "Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium." in: Histochemistry and cell biology, Vol. 136, Issue 6, pp. 617-36, (2011) (PubMed).

    Schauer, Janssen, Rimkus, Raggi, Feith, Friess, Theisen: "Microarray-based response prediction in esophageal adenocarcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 1, pp. 330-7, (2010) (PubMed).

  • Target
    EPH Receptor B3 (EPHB3)
    Alternative Name
    EPHB3 (EPHB3 Products)
    Background
    Full Gene Name: EPH receptor B3
    Synonyms: ETK2,HEK2,TYRO6
    Gene ID
    2049
    NCBI Accession
    NM_004443
    Pathways
    RTK Signaling
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