DHODH antibody (AA 32-140)

Catalog No. ABIN560602

Product Details anti-DHODH Antibody

Target: DHODH (Dihydroorotate Dehydrogenase (DHODH))

Binding Specificity: AA 32-140

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DHODH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant DHODH.

Sequence: GDERFYAEHL MPTLQGLLDP ESAHRLAVRF TSLGLLPRAR FQDSDMLEVR VLGHKFRNPV GIAAGFDKHG EAVDGLYKMG FGFVEIGSVT PKPQEGNPRP RVFRLPEDQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DHODH (NP_001352, 32 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 6E1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DHODH antibody (ABIN560602)

Lucas-Hourani, Dauzonne, Jorda, Cousin, Lupan, Helynck, Caignard, Janvier, André-Leroux, Khiar, Escriou, Desprès, Jacob, Munier-Lehmann, Tangy, Vidalain: "Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity." in: PLoS pathogens, Vol. 9, Issue 10, pp. e1003678, (2013) (PubMed).

Target Details for DHODH

Target: DHODH (Dihydroorotate Dehydrogenase (DHODH))

Alternative Name: DHODH (DHODH Products)

Background: Full Gene Name: dihydroorotate dehydrogenase
Synonyms: DHOdehase

Gene ID: 1723

NCBI Accession: NM_001361

Pathways: Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus