GADD45A antibody (AA 76-165)

Catalog No. ABIN560584

Product Details anti-GADD45A Antibody

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Binding Specificity: AA 76-165

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Proximity Ligation Assay (PLA)

Purpose: Mouse monoclonal antibody raised against a partial recombinant GADD45A.

Sequence: TLIQAFCCEN DINILRVSNP GRLAELLLLE TDAGPAASEG AEQPPDLHCV LVTNPHSSQW KDPALSQLIC FCRESRYMDQ WVPVINLPER

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GADD45A (AAH11757, 76 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3D12

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GADD45A antibody (ABIN560584)

Matteucci, Minutolo, Balestrieri, Marino-Merlo, Bramanti, Garaci, Macchi, Mastino: "Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis." in: Cell death & disease, Vol. 1, pp. e81, (2011) (PubMed).

Al-Romaih, Sadikovic, Yoshimoto, Wang, Zielenska, Squire: "Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 5, pp. 471-80, (2008) (PubMed).

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A (GADD45A Products)

Synonyms: MGC53491 antibody, zgc:91795 antibody, gadd45a antibody, GADD45A antibody, ddit1 antibody, gadd45 antibody, GADD45 antibody, AA545191 antibody, Ddit1 antibody, DDIT1 antibody, Gadd45 antibody, growth arrest and DNA damage inducible alpha L homeolog antibody, growth arrest and DNA-damage-inducible, alpha, b antibody, growth arrest and DNA damage inducible alpha antibody, growth arrest and DNA damage-inducible protein 45 antibody, growth arrest and DNA-damage-inducible 45 alpha antibody, growth arrest and DNA-damage-inducible, alpha antibody, gadd45a.L antibody, gadd45ab antibody, GADD45A antibody, gadd45a antibody, GADD45 antibody, Gadd45a antibody

Background: Full Gene Name: growth arrest and DNA-damage-inducible, alpha
Synonyms: DDIT1,GADD45

Gene ID: 1647

Pathways: p53 Signaling, Cell Division Cycle