NK2 Homeobox 5 antibody (AA 1-324)

Catalog No. ABIN560515

Product Details anti-NK2 Homeobox 5 Antibody

Target: NK2 Homeobox 5 (NKX2-5)

Binding Specificity: AA 1-324

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NK2 Homeobox 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant NKX2-5.

Sequence: MFPSPALTPT PFSVKDILNL EQQQRSLAAA GELSARLEAT LAPSSCMLAA FKPEAYAGPE AAAPGLPELR AELGRAPSPA KCASAFPAAP AFYPRAYSDP DPAKDPRAEK KELCALQKAV ELEKTEADNA ERPRARRRRK PRVLFSQAQV YELERRFKQQ RYLSAPERDQ LASVLKLTST QVKIWFQNRR YKCKRQRQDQ TLELVGLPPP PPPPARRIAV PVLVRDGKPC LGDSAPYAPA YGVGLNPYGY NAYPAYPGYG GAACSPGYSC TAAYPAGPSP AQPATAAANN NFVNFGVGDL NAVQSPGIPQ SNSGVSTLHG IRAW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NKX2-5 (AAH25711, 1 a.a. ~ 324 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1E4-G5

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-NK2 Homeobox 5 antibody (ABIN560515)

Costa, Lee, Furtado, Xin, Sparrow, Martinez, Dunwoodie, Kurtenbach, Mohun, Rosenthal, Harvey: "Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5." in: PLoS ONE, Vol. 6, Issue 9, pp. e24812, (2011) (PubMed).

Yadava, Frenzel-McCardell, Yu, Srinivasan, Tucker, Puymirat, Thornton, Prall, Harvey, Mahadevan: "RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression." in: Nature genetics, Vol. 40, Issue 1, pp. 61-8, (2007) (PubMed).

Target Details for NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Alternative Name: NKX2-5 (NKX2-5 Products)

Background: Full Gene Name: NK2 transcription factor related, locus 5 (Drosophila)
Synonyms: CHNG5,CSX,CSX1,NKX2.5,NKX2E,NKX4-1

Gene ID: 1482

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development