M-CSF/CSF1 antibody (AA 33-132)

Catalog No. ABIN560496

Product Details anti-M-CSF/CSF1 Antibody

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Binding Specificity: AA 33-132

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This M-CSF/CSF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant CSF1.

Sequence: EEVSEYCSHM IGSGHLQSLQ RLIDSQMETS CQITFEFVDQ EQLKDPVCYL KKAFLLVQDI MEDTMRFRDN TPNAIAIVQL QELSLRLKSC FTKDYEEHDK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CSF1 (AAH21117, 33 a.a. ~ 132 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1A9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-M-CSF/CSF1 antibody (ABIN560496)

Cimino, De Pittà, Orso, Zampini, Casara, Penna, Quaglino, Forni, Damasco, Pinatel, Ponzone, Romualdi, Brisken, De Bortoli, Biglia, Provero, Lanfranchi, Taverna: "miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 3, pp. 1223-35, (2013) (PubMed).

Lawlor, Nazarian, Lacomis, Tempst, Villanueva: "Pathway-based biomarker search by high-throughput proteomics profiling of secretomes." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1489-503, (2009) (PubMed).

Target Details for M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Alternative Name: CSF1 (CSF1 Products)

Background: Full Gene Name: colony stimulating factor 1 (macrophage)
Synonyms: MCSF,MGC31930

Gene ID: 1435

Pathways: RTK Signaling