Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CRX antibody (AA 1-95)

CRX Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4G11 unconjugated
Catalog No. ABIN560473
  • Target See all CRX Antibodies
    CRX (Cone-Rod Homeobox (CRX))
    Binding Specificity
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-95
    Reactivity
    • 24
    • 23
    • 22
    Human
    Host
    • 32
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 35
    • 2
    Monoclonal
    Conjugate
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRX antibody is un-conjugated
    Application
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant CRX.
    Sequence
    MMAYMNPGPH YSVNALALSG PSVDLMHQAV PYPSAPRKQR RERTTFTRSQ LEELEALFAK TQYPDVYARE EVALKINLPE SRVQVWFKNR RAKCR
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    CRX (NP_000545, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4G11
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Khan, Walters, Li, Thomas, Miller, Zhang, Sciallis, Liu, Dlouhy, Fort, Archer, Demirci, Dou, Rao: "Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 11, pp. 1278-90, (2015) (PubMed).

    Reichman, Goureau: "Production of Retinal Cells from Confluent Human iPS Cells." in: Methods in molecular biology (Clifton, N.J.), Vol. 1357, pp. 339-51, (2015) (PubMed).

    Tran, Zhang, Zhang, Huecker, Hennig, Chen: "Mechanistically distinct mouse models for CRX-associated retinopathy." in: PLoS genetics, Vol. 10, Issue 2, pp. e1004111, (2014) (PubMed).

    Jayaram, Jones, Eastlake, Cottrill, Becker, Wiseman, Khaw, Limb: "Transplantation of photoreceptors derived from human Muller glia restore rod function in the P23H rat." in: Stem cells translational medicine, Vol. 3, Issue 3, pp. 323-33, (2014) (PubMed).

    Reichman, Terray, Slembrouck, Nanteau, Orieux, Habeler, Nandrot, Sahel, Monville, Goureau: "From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 23, pp. 8518-23, (2014) (PubMed).

    Xie, Zhang, Hashimoto, Tien, Chen, Ge, Yang: "Differentiation of retinal ganglion cells and photoreceptor precursors from mouse induced pluripotent stem cells carrying an Atoh7/Math5 lineage reporter." in: PLoS ONE, Vol. 9, Issue 11, pp. e112175, (2014) (PubMed).

    Carr, Vugler, Yu, Semo, Coffey, Moss, Greenwood: "The expression of retinal cell markers in human retinal pigment epithelial cells and their augmentation by the synthetic retinoid fenretinide." in: Molecular vision, Vol. 17, pp. 1701-15, (2011) (PubMed).

    Sakagami, Gan, Yang: "Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 21, pp. 6932-44, (2009) (PubMed).

    Esumi, Kachi, Hackler, Masuda, Yang, Campochiaro, Zack: "BEST1 expression in the retinal pigment epithelium is modulated by OTX family members." in: Human molecular genetics, Vol. 18, Issue 1, pp. 128-41, (2008) (PubMed).

    Peng, Chen: "Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation." in: Human molecular genetics, Vol. 16, Issue 20, pp. 2433-52, (2007) (PubMed).

  • Target
    CRX (Cone-Rod Homeobox (CRX))
    Alternative Name
    CRX (CRX Products)
    Synonyms
    Xotx5 antibody, Xotx5b antibody, cord2 antibody, crd antibody, otx5 antibody, otx5b antibody, rx antibody, CRX antibody, crx antibody, otx5-b antibody, CORD2 antibody, CRD antibody, LCA7 antibody, OTX3 antibody, Crx1 antibody, otx5-A antibody, cone-rod homeobox antibody, cone-rod homeobox L homeolog antibody, cone-rod homeobox S homeolog antibody, crx antibody, CRX antibody, Crx antibody, crx.L antibody, crx.S antibody
    Background
    Full Gene Name: cone-rod homeobox
    Synonyms: CORD2,CRD,LCA7,OTX3
    Gene ID
    1406
    NCBI Accession
    NM_000554
You are here:
Support