CETN3 antibody (AA 1-100)

Catalog No. ABIN560341

Product Details anti-CETN3 Antibody

Target: CETN3 (Centrin, EF-Hand Protein, 3 (CETN3))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CETN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant CETN3.

Sequence: MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CETN3 (AAH05383, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3E6

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CETN3 antibody (ABIN560341)

Doobin, Kemal, Dantas, Vallee: "Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages." in: Nature communications, Vol. 7, pp. 12551, (2016) (PubMed).

Antonczak, Mullee, Wang, Comartin, Inoue, Pelletier, Morrison: "Opposing effects of pericentrin and microcephalin on the pericentriolar material regulate CHK1 activation in the DNA damage response." in: Oncogene, (2015) (PubMed).

Mäki-Jouppila, Laine, Rehnberg, Narvi, Tiikkainen, Hukasova, Halonen, Lindqvist, Kallio, Poso, Kallio: "Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na." in: Molecular cancer therapeutics, Vol. 13, Issue 5, pp. 1054-66, (2014) (PubMed).

Kaczmarczyk, Sullivan: "CENP-W plays a role in maintaining bipolar spindle structure." in: PLoS ONE, Vol. 9, Issue 10, pp. e106464, (2014) (PubMed).

Löffler, Fechter, Liu, Poppelreuther, Krämer: "DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites." in: Oncogene, Vol. 32, Issue 24, pp. 2963-72, (2013) (PubMed).

Schaub, Stearns: "The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content." in: Molecular biology of the cell, Vol. 24, Issue 4, pp. 453-64, (2013) (PubMed).

Patel, Scrimieri, Ghosh, Zhong, Kim, Ren, Morgan, Iacobuzio-Donahue, Pandey, Kern: "FAM190A deficiency creates a cell division defect." in: The American journal of pathology, Vol. 183, Issue 1, pp. 296-303, (2013) (PubMed).

Dantas, Daly, Conroy, Tomas, Wang, Lalor, Dockery, Ferrando-May, Morrison: "Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair." in: PLoS ONE, Vol. 8, Issue 7, pp. e68487, (2013) (PubMed).

Inanç, Pütz, Lalor, Dockery, Kuriyama, Gergely, Morrison: "Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells." in: Molecular biology of the cell, Vol. 24, Issue 17, pp. 2645-54, (2013) (PubMed).

Sir, Pütz, Daly, Morrison, Dunning, Kilmartin, Gergely: "Loss of centrioles causes chromosomal instability in vertebrate somatic cells." in: The Journal of cell biology, Vol. 203, Issue 5, pp. 747-56, (2013) (PubMed).

McIntyre, Lakshminarasimhan Chavali, Ismail, Carragher, Sanchez-Andrade, Forment, Fu, Del Castillo Velasco-Herrera, Edwards, van der Weyden, Yang, Ramirez-Solis, Estabel, Gallagher, Logan, Arends et al.: "Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome. ..." in: PLoS genetics, Vol. 8, Issue 11, pp. e1003022, (2012) (PubMed).

Conroy, Saladino, Dantas, Lalor, Dockery, Morrison: "C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 20, pp. 3769-78, (2012) (PubMed).

Dantas, Wang, Lalor, Dockery, Morrison: "Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins." in: The Journal of cell biology, Vol. 193, Issue 2, pp. 307-18, (2011) (PubMed).

Sir, Barr, Nicholas, Carvalho, Khurshid, Sossick, Reichelt, DSantos, Woods, Gergely: "A primary microcephaly protein complex forms a ring around parental centrioles." in: Nature genetics, Vol. 43, Issue 11, pp. 1147-53, (2011) (PubMed).

Barr, Kilmartin, Gergely: "CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response." in: The Journal of cell biology, Vol. 189, Issue 1, pp. 23-39, (2010) (PubMed).

Fabian, Fearnhead: "TPCK targets elements of mitotic spindle and induces cell cycle arrest in prometaphase." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 458-64, (2010) (PubMed).

Target Details for CETN3

Target: CETN3 (Centrin, EF-Hand Protein, 3 (CETN3))

Alternative Name: CETN3 (CETN3 Products)

Synonyms: CETN3 antibody, MGC142353 antibody, im:6894264 antibody, zgc:109972 antibody, 23.m05892 antibody, MmCEN3 antibody, CDC31 antibody, CEN3 antibody, centrin 3 L homeolog antibody, centrin 3 antibody, centrin 3, putative antibody, cetn3.L antibody, CETN3 antibody, cetn3 antibody, TA19510 antibody, BBOV_IV005160 antibody, CC1G_00652 antibody, Cetn3 antibody

Background: Full Gene Name: centrin, EF-hand protein, 3 (CDC31 homolog, yeast)
Synonyms: CEN3,MGC12502,MGC138245

Gene ID: 1070