BLK antibody (AA 1-90)
BLK
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
7A12
unconjugated
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Target
See all BLK Antibodies
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BLK
(B Lymphoid Tyrosine Kinase (BLK))
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Binding Specificity
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AA 1-90
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Reactivity
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Human
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Host
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Mouse
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Clonality
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Monoclonal
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Conjugate
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This BLK antibody is un-conjugated
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Application
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Western Blotting (WB), ELISA
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Purpose
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Mouse monoclonal antibody raised against a partial recombinant BLK.
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Sequence
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MGLVSSKKPD KEKPIKEKDK GQWSPLKVSA QDKDAPPLPP LVVFNHLTPP PPDEHLDEDK HFVVALYDYT AMNDRDLQML KGEKLQVLKG
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Cross-Reactivity
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Human, Mouse, Rat
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Characteristics
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Antibody Reactive Against Recombinant Protein.
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Immunogen
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BLK (AAH07371, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone
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7A12
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Isotype
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IgG1
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Top Product
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Discover our top product BLK Primary Antibody
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Buffer
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In 1x PBS, pH 7.4
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Handling Advice
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Aliquot to avoid repeated freezing and thawing.
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Storage
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-20 °C
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Storage Comment
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Bernal-Quirós, Wu, Alarcón-Riquelme, Castillejo-López: "BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling." in: PLoS ONE, Vol. 8, Issue 3, pp. e59842, (2013) (PubMed).
Castillejo-López, Delgado-Vega, Wojcik, Kozyrev, Thavathiru, Wu, Sánchez, Pöllmann, López-Egido, Fineschi, Domínguez, Lu, James, Merrill, Kelly, Kaufman, Moser, Gilkeson, Frostegård, Pons-Estel et al.: "Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. ..." in: Annals of the rheumatic diseases, Vol. 71, Issue 1, pp. 136-42, (2011) (PubMed).
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Target
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BLK
(B Lymphoid Tyrosine Kinase (BLK))
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Alternative Name
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BLK (BLK Products)
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Synonyms
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bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody
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Background
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Full Gene Name: B lymphoid tyrosine kinase
Synonyms: MGC10442
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Gene ID
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640
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Pathways
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Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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