Biglycan antibody (AA 1-368)

Catalog No. ABIN560056

Product Details anti-Biglycan Antibody

Target: Biglycan (BGN)

Binding Specificity: AA 1-368

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Biglycan antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant BGN.

Sequence: MWPLWRLVSL LALSQALPFE QRGFWDFTLD DGPFMMNDEE ASGADTSGVL DPDSVTPTYS AMCPFGCHCH LRVVQCSDLG LKSVPKEISP DTTLLDLQNN DISELRKDDF KGLQHLYALV LVNNKISKIH EKAFSPLRKL QKLYISKNHL VEIPPNLPSS LVELRIHDNR IRKVPKGVFS GLRNMNCIEM GGNPLENSGF EPGAFDGLKL NYLRISEAKL TGIPKDLPET LNELHLDHNK IQAIELEDLL RYSKLYRLGL GHNQIRMIEN GSLSFLPTLR ELHLDNNKLA RVPSGLPDLK LLQVVYLHSN NITKVGVNDF CPMGFGVKRA YYNGISLFNN PVPYWEVQPA TFRCVTDRLA IQFGNYKK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BGN (AAH02416.1, 1 a.a. ~ 368 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4E1-1G7

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Biglycan antibody (ABIN560056)

Zhang, Lee, Young, Wang: "The Small Leucine-Rich Proteoglycan BGN Accumulates in CADASIL and Binds to NOTCH3." in: Translational stroke research, Vol. 6, Issue 2, pp. 148-55, (2015) (PubMed).

Target Details for Biglycan

Target: Biglycan (BGN)

Alternative Name: BGN (BGN Products)

Background: Full Gene Name: biglycan
Synonyms: DSPG1,PG-S1,PGI,SLRR1A

Gene ID: 633

Pathways: Glycosaminoglycan Metabolic Process