beta-2 Microglobulin antibody (AA 1-119)

Catalog No. ABIN560019

Product Details anti-beta-2 Microglobulin Antibody

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Binding Specificity: AA 1-119

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta-2 Microglobulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi), Proximity Ligation Assay (PLA)

Purpose: Mouse monoclonal antibody raised against a full length recombinant B2M.

Sequence: MSRSVALAVL ALLSLSGLEA IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: B2M (AAH32589, 1 a.a. ~ 119 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3F9-2C2

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-beta-2 Microglobulin antibody (ABIN560019)

Cebrián, Zucca, Mauri, Steinbeck, Studer, Scherzer, Kanter, Budhu, Mandelbaum, Vonsattel, Zecca, Loike, Sulzer: "MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration." in: Nature communications, Vol. 5, pp. 3633, (2014) (PubMed).

Target Details for beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Alternative Name: B2M (B2M Products)

Background: Full Gene Name: beta-2-microglobulin
Synonyms:

Gene ID: 567

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process