RHOA antibody (AA 1-193)

Catalog No. ABIN559931

Product Details anti-RHOA Antibody

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Binding Specificity: AA 1-193

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RHOA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a full length recombinant RHOA.

Sequence: MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPVK PEEGRDMANR IGAFGYMECS AKTKDGVREV FEMATRAALQ ARRGKKKSGC LVL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RHOA (AAH01360, 1 a.a. ~ 193 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1B12

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RHOA antibody (ABIN559931)

Jeong, Park, Kim, Kim, Ahn, Bae, Kim, Kim, Im, Lee, Kwon, Baek: "RhoA is associated with invasion and poor prognosis in colorectal cancer." in: International journal of oncology, Vol. 48, Issue 2, pp. 714-22, (2015) (PubMed).

Ma, Liu, Zhang, Geng, Li: "Relationship of RhoA signaling activity with ezrin expression and its significance in the prognosis for breast cancer patients." in: Chinese medical journal, Vol. 126, Issue 2, pp. 242-7, (2013) (PubMed).

Chang, Gottlieb: "Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 8, Issue 6, pp. 2123-30, (1988) (PubMed).

Target Details for RHOA

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Alternative Name: RHOA (RHOA Products)

Background: Full Gene Name: ras homolog gene family, member A
Synonyms: ARH12,ARHA,RHO12,RHOH12

Gene ID: 387

Pathways: Microtubule Dynamics, WNT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome