Survivin antibody (AA 1-100)
BIRC5
Reactivity: Human
WB, ELISA, IF, IP, RNAi
Host: Mouse
Monoclonal
5B10
unconjugated
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Target
See all Survivin (BIRC5) Antibodies
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Survivin (BIRC5)
(Baculoviral IAP Repeat-Containing 5 (BIRC5))
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Binding Specificity
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AA 1-100
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Reactivity
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Human
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Host
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Mouse
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Clonality
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Monoclonal
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Conjugate
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This Survivin antibody is un-conjugated
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Application
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)
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Purpose
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Mouse monoclonal antibody raised against a partial recombinant BIRC5.
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Sequence
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MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE
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Cross-Reactivity
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Human
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Characteristics
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Antibody Reactive Against Recombinant Protein.
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Immunogen
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BIRC5 (NP_001159, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone
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5B10
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Isotype
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IgG2a
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Top Product
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Discover our top product BIRC5 Primary Antibody
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Buffer
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In 1x PBS, pH 7.4
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Handling Advice
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Aliquot to avoid repeated freezing and thawing.
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Storage
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-20 °C
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Storage Comment
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Horowitz, Ajayi, Kulasekaran, Rogers, White, Townsend, White, Nho, Higgins, Huang, Sisson: "Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 158-69, (2011) (PubMed).
Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: "The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression." in: Molecular biology of the cell, Vol. 21, Issue 16, pp. 2953-65, (2010) (PubMed).
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Target
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Survivin (BIRC5)
(Baculoviral IAP Repeat-Containing 5 (BIRC5))
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Alternative Name
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BIRC5 (BIRC5 Products)
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Background
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Full Gene Name: baculoviral IAP repeat-containing 5
Synonyms: API4,EPR-1
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Gene ID
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332
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NCBI Accession
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NM_001168
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Pathways
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Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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