Survivin antibody (AA 1-100)

Catalog No. ABIN559893

Product Details anti-Survivin Antibody

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant BIRC5.

Sequence: MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BIRC5 (NP_001159, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 5B10

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Survivin antibody (ABIN559893)

Horowitz, Ajayi, Kulasekaran, Rogers, White, Townsend, White, Nho, Higgins, Huang, Sisson: "Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 158-69, (2011) (PubMed).

Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: "The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression." in: Molecular biology of the cell, Vol. 21, Issue 16, pp. 2953-65, (2010) (PubMed).

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: BIRC5 (BIRC5 Products)

Synonyms: AP14 antibody, API4 antibody, EPR-1 antibody, AAC-11 antibody, Api4 antibody, TIAP antibody, survivin40 antibody, bir5a antibody, survivin antibody, BIR1 antibody, Su2 antibody, XBIR1 antibody, XSurvivin1 antibody, Xsvv1 antibody, api4 antibody, bir1-A antibody, epr-1 antibody, svv1 antibody, xSurvivin antibody, xsurv antibody, Su1 antibody, birc5.2 antibody, svv2 antibody, xSurvivin2 antibody, bir5b antibody, SIX antibody, birc5.2-a antibody, birc5.2-b antibody, baculoviral IAP repeat containing 5 antibody, baculoviral IAP repeat-containing 5 antibody, baculoviral IAP repeat containing 5a antibody, baculoviral IAP repeat-containing 5, gene 1 L homeolog antibody, baculoviral IAP repeat containing 5 L homeolog antibody, baculoviral IAP repeat containing 5b antibody, baculoviral IAP repeat containing 5 S homeolog antibody, BIRC5 antibody, Birc5 antibody, birc5a antibody, birc5.1.L antibody, birc5.2.L antibody, birc5b antibody, birc5.2.S antibody

Background: Full Gene Name: baculoviral IAP repeat-containing 5
Synonyms: API4,EPR-1

Gene ID: 332

NCBI Accession: NM_001168

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding