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SETDB2 antibody

SETDB2 Reactivity: Human, Mouse, Rabbit WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5596921
  • Target See all SETDB2 Antibodies
    SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
    Reactivity
    • 18
    • 16
    • 1
    • 1
    Human, Mouse, Rabbit
    Host
    • 27
    • 4
    • 1
    Rabbit
    Clonality
    • 29
    • 4
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETDB2 antibody is un-conjugated
    Application
    • 25
    • 13
    • 13
    • 9
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity (Details)
    Expect reactivity with Setdb2 from mouse and human sources. Reactivity against homologues from other sources is not known.
    Purification
    This Protein A purified antibody is directed against mouse Setdb2. The product was purified from monospecific antiserum by Protein A affinity chromatography.
    Immunogen

    Immunogen: Setdb2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a full legnth protein corresponding to mouse Setdb2.

    Immunogen Type: Recombinant Protein

    Isotype
    IgG
    Top Product
    Discover our top product SETDB2 Primary Antibody
  • Application Notes

    Application Note: Anti-Setdb2 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80.6 kDa in size corresponding to Setdb2 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:10,000 - 1:100,000

    ELISA Dilution: 1:2,500 - 1:10,000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.98 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • Target
    SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
    Alternative Name
    Setdb2 (SETDB2 Products)
    Synonyms
    C13orf4 antibody, CLLD8 antibody, CLLL8 antibody, KMT1F antibody, Clld8 antibody, Gm293 antibody, SET domain bifurcated 2 antibody, SET domain, bifurcated 2 antibody, SETDB2 antibody, Setdb2 antibody
    Background

    Synonyms: Histone-lysine N-methyltransferase SETDB2, SET domain bifurcated 2, Setdb2 antibody, Gm293

    Background: Setdb2 is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). Setdb2 and the neighboring gene Phf11 were linked to familial atopy/ asthma and are in a "critical region" commonly deleted in CLL. Setdb2 is a candidate histone methyltransferase as a member of the Su(var) 3-9 family of SET domain-containing enzymes. Other predicted domains in Setdb2 include a methylcytosine binding domain and a large bifurcation domain interrupting the putative histone methyltransferase (SET) domain whose function is unknown. Anti-Setdb2 antibody is ideal for researchers interested in Cancer Research and Epigenetics Research.

    Gene Name: Setdb2

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