HDAC10 antibody (AA 500-550)

Catalog No. ABIN5596721

Supplier Product No.: 600-401-j77

Product Details anti-HDAC10 Antibody

Target: HDAC10 (Histone Deacetylase 10 (HDAC10))

Binding Specificity: AA 500-550

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Supplier Product No.: 600-401-j77

Supplier: Rockland

Purpose: HDAC10 (internal) Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with human based on 100 % sequence homology.

Characteristics: Synonyms: rabbit anti-HDAC-10 antibody, HDAC10, HDAC 10, HD 10 antibody, histone deacetylase 10 antibody, Histone deacetylase-10, HD10 antibody

Purification: Anti-HDAC10 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterility: Sterile filtered

Immunogen:

Immunogen: Anti-HDAC10 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region surrounding 500-550aa of human HDAC10 protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-HDAC10 antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~71 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for HDAC10

Target: HDAC10 (Histone Deacetylase 10 (HDAC10))

Alternative Name: HDAC10 (HDAC10 Products)

Background: Background: HDAC10 is located in the nucleus and cytoplasm, expressed most highly in the liver, spleen, pancreas and kidney. It is responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). The result of deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Anti-HDAC10 therefore is ideal for investigators interested in Stem Cells or Epigenetics and Nuclear Signaling research.

UniProt: Q969S8