FIL1h antibody
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- Target See all FIL1h products
- FIL1h (Interleukin 1 eta (FIL1h))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FIL1h antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Recognizes human IL-36beta.
- Cross-Reactivity
- Human
- No Cross-Reactivity
- Mouse (Murine)
- Cross-Reactivity (Details)
- Does not cross-react with mouse IL-36beta and IL-36gamma.
- Immunogen
- Recombinant human IL-36beta.
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anti-Interleukin 1 eta (FIL1h) (C-Term) antibody
FIL1h Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 1 eta (FIL1h) (AA 1-30), (N-Term) antibodyFIL1h Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB22631 unconjugated
anti-Interleukin 1 eta (FIL1h) (AA 1-157) antibodyFIL1h Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E4 unconjugated
anti-Interleukin 1 eta (FIL1h) (AA 1-157) antibodyFIL1h Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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- Target
- FIL1h (Interleukin 1 eta (FIL1h))
- Alternative Name
- IL-36beta (FIL1h Products)
- Synonyms
- 2310043N20Rik antibody, Il36b antibody, FIL1 antibody, FIL1-(ETA) antibody, FIL1H antibody, FILI-(ETA) antibody, IL-1F8 antibody, IL-1H2 antibody, IL1-ETA antibody, IL1F8 antibody, IL1H2 antibody, Il1f8 antibody, interleukin 1 family, member 8 antibody, interleukin 36 beta antibody, interleukin 36, beta antibody, Il1f8 antibody, IL36B antibody, Il36b antibody
- Background
- IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
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