Recombinant TNFSF4 (Oxelumab Biosimilar) antibody
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- Target See all TNFSF4 (Oxelumab Biosimilar) products
- TNFSF4 (Oxelumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
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Human
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Clonality
- Monoclonal
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Conjugate
- This TNFSF4 (Oxelumab Biosimilar) antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificity
- Recognizes human OX40L.
- Cross-Reactivity
- Human
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.001EU/μg
- Immunogen
- Recombinant human OX40L.
- Clone
- R4930
- Isotype
- IgG1
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- Comment
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This antibody is a biosimilar generically called Oxelumab (CAS 1186098-83-8) and originally developed by Genentech. Oxelumab is a OX40 ligand blocker designed for the prevention of allergen-induced airway inflammation in adults with mild asthma. Potentially other application areas are transplantation and autoimmunity research or protection against inflammation-driven fibrosis.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS.
- Preservative
- Without preservative
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 3 months after receipt when stored at +4°C. - Expiry Date
- 12 months
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- Target
- TNFSF4 (Oxelumab Biosimilar)
- Abstract
- TNFSF4 (Oxelumab Biosimilar) Products
- Synonyms
- CD134L antibody, CD252 antibody, GP34 antibody, OX-40L antibody, OX4OL antibody, TXGP1 antibody, TNF superfamily member 4 antibody, TNFSF4 antibody
- Target Type
- Biosimilar
- Background
- OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
- UniProt
- P23510
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