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Cytochrome C antibody

CYCS Reactivity: Human, Rat, Mouse WB, IHC (p), IF (p), IF (cc) Host: Rabbit Monoclonal 1F10 unconjugated
Catalog No. ABIN5557297
  • Target See all Cytochrome C (CYCS) Antibodies
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Reactivity
    • 139
    • 111
    • 90
    • 44
    • 32
    • 23
    • 22
    • 19
    • 18
    • 16
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 83
    • 70
    • 6
    • 1
    Rabbit
    Clonality
    • 80
    • 79
    • 1
    Monoclonal
    Conjugate
    • 92
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cytochrome C antibody is un-conjugated
    Application
    • 123
    • 47
    • 37
    • 34
    • 32
    • 30
    • 26
    • 21
    • 13
    • 13
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    Recombinant human Cytochrome C protein, full length.
    Clone
    1F10
    Isotype
    IgG
    Top Product
    Discover our top product CYCS Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Alternative Name
    Cytochrome C (CYCS Products)
    Background

    Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS

    Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

    Gene ID
    54205
    UniProt
    P99999
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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