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Cyclin E1 antibody

CCNE1 Reactivity: Human, Mouse IHC (p), IF (cc) Host: Rabbit Monoclonal 4H7 unconjugated
Catalog No. ABIN5557295
  • Target See all Cyclin E1 (CCNE1) Antibodies
    Cyclin E1 (CCNE1)
    Reactivity
    • 145
    • 35
    • 33
    • 3
    • 2
    • 2
    • 2
    Human, Mouse
    Host
    • 120
    • 24
    • 1
    Rabbit
    Clonality
    • 115
    • 30
    Monoclonal
    Conjugate
    • 80
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Cyclin E1 antibody is un-conjugated
    Application
    • 98
    • 49
    • 47
    • 43
    • 32
    • 27
    • 19
    • 13
    • 12
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human, Mouse
    Purification
    Purified by Protein A.
    Immunogen
    Synthetic peptide derive from human cyclin e1
    Clone
    4H7
    Isotype
    IgG
    Top Product
    Discover our top product CCNE1 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Cyclin E1 (CCNE1)
    Alternative Name
    Cyclin E1 (CCNE1 Products)
    Synonyms
    CCNE1 antibody, ccne antibody, cyclinE antibody, CCNE antibody, AW538188 antibody, CycE1 antibody, CYCLE antibody, Ccne antibody, cyce2 antibody, cycE3 antibody, cyce antibody, fa18e07 antibody, wu:fa18e07 antibody, cyclin E1 antibody, cyclin E1 L homeolog antibody, cyclin E1 S homeolog antibody, CCNE1 antibody, ccne1 antibody, Ccne1 antibody, ccne1.L antibody, ccne1.S antibody
    Background

    Synonyms: Cyclin E1 phospho T77, p-Cyclin E1 phospho T77, Cyclin E1 Thr77, CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E.

    Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

    Gene ID
    898
    UniProt
    P24864
    Pathways
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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