Cyclin D3 antibody
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- Target See all Cyclin D3 (CCND3) Antibodies
- Cyclin D3 (CCND3)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Cyclin D3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant human Cyclin D3 protein, around C-terminal 200aa.
- Clone
- 4A8
- Isotype
- IgG
- Top Product
- Discover our top product CCND3 Primary Antibody
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anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 Reactivity: Human WB, ELISA, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 121-220) antibodyCCND3 Reactivity: Human, Rabbit WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (pThr283) antibodyCCND3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 136-292) antibodyCCND3 Reactivity: Human, Rat WB, FACS Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 252-281), (C-Term) antibodyCCND3 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB43029 unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reactivity: Human WB, IHC (p), IF Host: Mouse Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Sheep, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reactivity: Human WB, ELISA, IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 33-66), (N-Term) antibodyCCND3 Reactivity: Rat WB Host: Rabbit Polyclonal RB43404 unconjugated
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- Application Notes
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WB 1:300-5000
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- Cyclin D3 (CCND3)
- Alternative Name
- Cyclin D3 (CCND3 Products)
- Synonyms
- zgc:103502 antibody, CCND3 antibody, 9230106B05Rik antibody, AA682053 antibody, AL024085 antibody, AW146355 antibody, C78795 antibody, cyclin D3 antibody, ccnd3 antibody, CCND3 antibody, Ccnd3 antibody
- Background
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Synonyms: G1/S-specific cyclin-D3, CCND3
Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
- Gene ID
- 896
- UniProt
- P30281
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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