ARAF antibody

Catalog No. ABIN5557283

Product Details anti-ARAF Antibody

Target: ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ARAF antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant human A-RAF protein, around 150-300aa.

Clone: 24D1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ARAF

Target: ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))

Alternative Name: A-RAF (ARAF Products)

Synonyms: zgc:92074 antibody, wu:fk45h07 antibody, ARAF antibody, a-raf antibody, araf antibody, araf1 antibody, pks2 antibody, rafa1 antibody, A-RAF antibody, ARAF1 antibody, PKS2 antibody, RAFA1 antibody, 1200013E08Rik antibody, A-Raf antibody, AW495444 antibody, Araf1 antibody, A-Raf proto-oncogene, serine/threonine kinase antibody, A-Raf proto-oncogene, serine/threonine kinase L homeolog antibody, A-Raf proto-oncogene, serine/threonine kinase S homeolog antibody, Araf proto-oncogene, serine/threonine kinase antibody, araf antibody, ARAF antibody, araf.L antibody, araf.S antibody, Araf antibody

Background:

Synonyms: Serine/threonine-protein kinase A-Raf, ARAF, Proto-oncogene A-Raf, Proto-oncogene A-Raf-1, Proto-oncogene Pks, ARAF1, PKS, PKS2

Background: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation.

Gene ID: 369

UniProt: P10398

Pathways: MAPK Signaling, RTK Signaling, Hepatitis C