DOC2A antibody (AA 652-749)
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- Target See all DOC2A Antibodies
- DOC2A (Double C2-Like Domains, alpha (DOC2A))
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Binding Specificity
- AA 652-749
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DOC2A antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purpose
- DOC2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli.
- Clone
- 2H7C4
- Isotype
- IgG1
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anti-Double C2-Like Domains, alpha (DOC2A) (AA 277-306) antibody
DOC2A Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB32573 unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 1-400) antibodyDOC2A Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 233-246) antibodyVerified DOC2A Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 1-400) antibodyDOC2A Reactivity: Human ELISA Host: Mouse Monoclonal 3C11 unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 284-314), (Middle Region) antibodyDOC2A Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- DOC2A (Double C2-Like Domains, alpha (DOC2A))
- Alternative Name
- DOC2 (DOC2A Products)
- Synonyms
- DOC2A antibody, doc2-A antibody, Doc2 antibody, double C2 domain alpha antibody, double C2-like domains, alpha antibody, double C2, alpha antibody, DOC2A antibody, doc2a antibody, Doc2a antibody
- Background
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Description: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases: DAB2, DOC-2
- Molecular Weight
- 82.4kDa
- Gene ID
- 1601
- HGNC
- 5899
- UniProt
- P98082
- Pathways
- Synaptic Vesicle Exocytosis
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