CBX5 antibody (AA 1-191)

Catalog No. ABIN5542711

Product Details anti-CBX5 Antibody

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Binding Specificity: AA 1-191

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: CBX5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E. Coli.

Clone: 1B10B2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: CBX5 (CBX5 Products)

Synonyms: HP1 antibody, HP1A antibody, id:ibd2026 antibody, wu:fc63e02 antibody, wu:fe47g12 antibody, wu:fi03h05 antibody, zgc:158601 antibody, CBX5 antibody, cbx5 antibody, MGC64354 antibody, 2610029O15Rik antibody, C75991 antibody, Hp1a antibody, Hp1alpha antibody, chromobox 5 antibody, chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, chromobox 5 S homeolog antibody, CBX5 antibody, cbx5 antibody, Cbx5 antibody, cbx5.S antibody

Background:

Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Aliases: HP1, HP1A, HEL25

Molecular Weight: 22.2kDa

Gene ID: 23468

HGNC: 23468

UniProt: P45973