Histone Cluster 2, H3c (HIST2H3C) (acLys27) antibody

Catalog No. ABIN5542709

Product Details

Target: Histone Cluster 2, H3c (HIST2H3C)

Binding Specificity: acLys27

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purpose: HIST2H3C (27Ac) Antibody

Purification: Purified antibody

Immunogen: Synthesized peptide of human HIST2H3C (AA: ATKAARK(Ac)SAPATGGV) .

Clone: 2D7B3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details

Target: Histone Cluster 2, H3c (HIST2H3C)

Alternative Name: HIST2H3C (HIST2H3C Products)

Synonyms: H3 antibody, H3.2 antibody, H3/M antibody, H3F2 antibody, H3FM antibody, H3FN antibody, histone cluster 2 H3 family member c antibody, HIST2H3C antibody

Background:

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy.

Aliases: H3, H3.2, H3/M, H3F2, H3FM, H3FN

Molecular Weight: 15.4kDa

Gene ID: 126961

HGNC: 126961

UniProt: Q71DI3