Complement C3c antibody (AA 1521-1649)
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- Target See all Complement C3c (C3C) products
- Complement C3c (C3C) (Complement Component C3c (C3C))
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Binding Specificity
- AA 1521-1649
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Complement C3c antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- C3C Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. Coli.
- Clone
- 4C6A8
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Complement C3c (C3C) (Complement Component C3c (C3C))
- Alternative Name
- C3C (C3C Products)
- Background
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Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Aliases: ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1, HEL-S-62p
- Molecular Weight
- 187.1kDa
- Gene ID
- 718
- HGNC
- 718
- UniProt
- P01024
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