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Complement C3c antibody (AA 1521-1649)

C3C Reactivity: Human ELISA, IHC, WB, ICC, FACS Host: Mouse Monoclonal 8B5H2 unconjugated
Catalog No. ABIN5542705
  • Target See all Complement C3c (C3C) products
    Complement C3c (C3C) (Complement Component C3c (C3C))
    Binding Specificity
    • 15
    • 3
    • 1
    AA 1521-1649
    Reactivity
    • 60
    • 28
    • 17
    • 15
    • 14
    • 12
    • 5
    • 4
    • 3
    • 1
    Human
    Host
    • 71
    • 27
    • 10
    • 9
    • 2
    • 1
    Mouse
    Clonality
    • 115
    • 3
    Monoclonal
    Conjugate
    • 36
    • 34
    • 16
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Complement C3c antibody is un-conjugated
    Application
    • 70
    • 50
    • 32
    • 30
    • 26
    • 19
    • 14
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. coli.
    Clone
    8B5H2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: , FCM:
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Helsby, Leader, Fenn, Gulsen, Bryant, Doughton, Sharpe, Whitley, Caunt, James, Pope, Kelly, Chalmers: "CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." in: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).

  • Target
    Complement C3c (C3C) (Complement Component C3c (C3C))
    Alternative Name
    C3C (C3C Products)
    Background

    Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.,

    Aliases: ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1, HEL-S-62p

    Molecular Weight
    187.1 kDa
    Gene ID
    718
    HGNC
    718
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