Complement C3c antibody (AA 1521-1649)
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- Target See all Complement C3c (C3C) products
- Complement C3c (C3C) (Complement Component C3c (C3C))
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Binding Specificity
- AA 1521-1649
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Complement C3c antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. coli.
- Clone
- 8B5H2
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: , FCM:
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." in: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).
: "
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CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." in: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).
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- Target
- Complement C3c (C3C) (Complement Component C3c (C3C))
- Alternative Name
- C3C (C3C Products)
- Background
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Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.,
Aliases: ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1, HEL-S-62p
- Molecular Weight
- 187.1 kDa
- Gene ID
- 718
- HGNC
- 718
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