Selenoprotein S antibody (AA 1-187)

Catalog No. ABIN5542695

Product Details anti-Selenoprotein S Antibody

Target: Selenoprotein S (SELS)

Binding Specificity: AA 1-187

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Selenoprotein S antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human VIMP (AA: 1-187) expressed in E. coli.

Clone: 5G4A10

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:50 - 1:250, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for Selenoprotein S

Target: Selenoprotein S (SELS)

Alternative Name: VIMP (SELS Products)

Synonyms: ADO15 antibody, SBBI8 antibody, SELS antibody, SEPS1 antibody, 1500011E07Rik antibody, C78786 antibody, H-4 antibody, H-47 antibody, H4 antibody, H47 antibody, Sels antibody, sg2 antibody, selenoprotein S antibody, SELENOS antibody, Selenos antibody

Background:

Description: This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms.,

Aliases: SELS, ADO15, SBBI8, SEPS1, AD-015

Molecular Weight: 21.2 kDa

Gene ID: 55829

HGNC: 55829

Pathways: Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome