MTRF1 antibody (AA 288-437)

Catalog No. ABIN5542689

Product Details anti-MTRF1 Antibody

Target: MTRF1 (Mitochondrial Translational Release Factor 1 (MTRF1))

Binding Specificity: AA 288-437

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: RF1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RF1 (AA: 288-437) expressed in E. Coli.

Clone: 4F9H12

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MTRF1

Target: MTRF1 (Mitochondrial Translational Release Factor 1 (MTRF1))

Alternative Name: RF1 (MTRF1 Products)

Synonyms: mrf1l antibody, mtrf1 antibody, mtrf1a antibody, MRF1 antibody, MTTRF1 antibody, RF1 antibody, A830062K05Rik antibody, MtRF-1 antibody, mitochondrial translation release factor 1 antibody, mitochondrial translational release factor 1 antibody, mitochondrial translational release factor 1 like antibody, MTRF1 antibody, LOC732994 antibody, mtrf1l antibody, Mtrf1 antibody

Background:

Description: This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

Aliases: ERF, ETF1, ERF1, TB3-1, D5S1995, SUP45L1

Molecular Weight: 49kDa

Gene ID: 2107

HGNC: 2107

UniProt: P62495