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Phospholipase C gamma 1 antibody (AA 39-181)
PLCG1
Reactivity: Human, Rat
WB, ELISA, IHC, ICC, FACS
Host: Mouse
Monoclonal
2F3D11
unconjugated
Product Details anti-Phospholipase C gamma 1 Antibody
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Target
See all Phospholipase C gamma 1 (PLCG1) Antibodies
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Binding Specificity
All epitopes for Phospholipase C gamma 1 antibodies
AA 39-181
Reactivity
All reactivities for Phospholipase C gamma 1 antibodies
Human, Rat
Host
All hosts for Phospholipase C gamma 1 antibodies
Mouse
Clonality
All clonalities for Phospholipase C gamma 1 antibodies
Monoclonal
Conjugate
All conjugates for Phospholipase C gamma 1 antibodies
This Phospholipase C gamma 1 antibody is un-conjugated
Application
All applications for Phospholipase C gamma 1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
Immunogen
Purified recombinant fragment of human PLCG1 (AA 39-181) expressed in E. Coli.
Clone
2F3D11
Isotype
IgG2a
Top Product
Discover our top product PLCG1 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.05 % sodium azide
Storage
4 °C,-20 °C
Storage Comment
4°C, -20°C for long term storage
Target Details for Phospholipase C gamma 1
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Target
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Alternative Name
PLCG1 (PLCG1 Products )
Synonyms
NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody
Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.,
Molecular Weight
89.8kDa
HGNC
29128
Pathways
RTK Signaling , WNT Signaling , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Thyroid Hormone Synthesis , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , Skeletal Muscle Fiber Development , G-protein mediated Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Interaction of EGFR with phospholipase C-gamma , VEGFR1 Specific Signals , VEGF Signaling
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