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Phospholipase C gamma 1 antibody (AA 1192-1291)

PLCG1 Reactivity: Human WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 3H1C10 unconjugated
Catalog No. ABIN5542681
  • Target See all Phospholipase C gamma 1 (PLCG1) Antibodies
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Binding Specificity
    • 34
    • 28
    • 13
    • 9
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1192-1291
    Reactivity
    • 138
    • 131
    • 120
    • 21
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 149
    • 21
    Mouse
    Clonality
    • 141
    • 29
    Monoclonal
    Conjugate
    • 77
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    This Phospholipase C gamma 1 antibody is un-conjugated
    Application
    • 114
    • 52
    • 38
    • 27
    • 26
    • 21
    • 20
    • 15
    • 9
    • 9
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purpose
    PLCG1 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PLCG1 (AA: 1192-1291) expressed in E. Coli.
    Clone
    3H1C10
    Isotype
    IgG1
    Top Product
    Discover our top product PLCG1 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Alternative Name
    PLCG1 (PLCG1 Products)
    Synonyms
    NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody
    Background

    Description: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

    Aliases: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1

    Molecular Weight
    148.5kDa
    Gene ID
    5335
    HGNC
    5335
    UniProt
    P19174
    Pathways
    RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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