TSHB antibody (AA 20-139)

Catalog No. ABIN5542677

Product Details anti-TSHB Antibody

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Binding Specificity: AA 20-139

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSHB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: TSHB Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TSHB (AA: 20-139) expressed in E. Coli.

Clone: 1D12G1

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Alternative Name: TSHB (TSHB Products)

Synonyms: TSH-B antibody, TSH-BETA antibody, TSHB antibody, thyroid stimulating hormone beta antibody, thyroid stimulating hormone, beta antibody, thyroid stimulating hormone, beta subunit antibody, TSHB antibody, Tshb antibody, tshb antibody

Background:

Description: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Aliases: TSH-B, TSH-BETA

Molecular Weight: 15.6kDa

Gene ID: 7252

HGNC: 7252

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism