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RAD50 antibody (AA 228-359)

RAD50 Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 5A8E5 unconjugated
Catalog No. ABIN5542670
  • Target See all RAD50 Antibodies
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Binding Specificity
    • 16
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 228-359
    Reactivity
    • 54
    • 51
    • 19
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 66
    • 4
    Mouse
    Clonality
    • 65
    • 5
    Monoclonal
    Conjugate
    • 34
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAD50 antibody is un-conjugated
    Application
    • 60
    • 23
    • 16
    • 16
    • 13
    • 13
    • 10
    • 10
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human RAD50 (AA: 228-359) expressed in E. coli.
    Clone
    5A8E5
    Isotype
    IgG1
    Top Product
    Discover our top product RAD50 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM:
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
    Alternative Name
    RAD50 (RAD50 Products)
    Synonyms
    NBSLD antibody, RAD502 antibody, hRad50 antibody, Mrell antibody, Rad50l antibody, 6339 antibody, CG6339 antibody, Dmel\\CG6339 antibody, Dmrad50 antibody, RAD50 antibody, Rad50 antibody, ATRAD50 antibody, DNA REPAIR-RECOMBINATION PROTEIN antibody, F22D22.28 antibody, F22D22_28 antibody, SPAP4C9.01c antibody, im:6906849 antibody, si:ch211-79h18.3 antibody, RAD50 double strand break repair protein antibody, CG6339 gene product from transcript CG6339-RE antibody, RAD50 homolog, double strand break repair protein L homeolog antibody, rad50 antibody, DNA repair protein RAD50 antibody, RAD50 homolog, double strand break repair protein antibody, DNA repair-recombination protein (RAD50) antibody, MRX complex DNA-binding subunit antibody, DNA repair protein Rad50 antibody, RAD50 recombination protein antibody, Rad50 DNA repair/recombination protein antibody, DNA repair protein rad-50 antibody, RAD50 antibody, Rad50 antibody, rad50 antibody, rad50.L antibody, LOC658288 antibody, LOC726642 antibody, rad-50 antibody
    Background

    Description: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.,

    Aliases: NBSLD, RAD502, hRad50

    Molecular Weight
    154 kDa
    Gene ID
    10111
    HGNC
    10111
    Pathways
    DNA Damage Repair, Protein targeting to Nucleus
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