SSH1 antibody (AA 1032-1044)
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- Target See all SSH1 Antibodies
- SSH1 (Slingshot Homolog 1 (SSH1))
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Binding Specificity
- AA 1032-1044
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SSH1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Immunogen
- Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. coli.
- Clone
- 6C11G9
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: , IHC: 1:200 - 1:1000, ICC: , FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- SSH1 (Slingshot Homolog 1 (SSH1))
- Alternative Name
- SLINGSHOT-1L (SSH1 Products)
- Synonyms
- AW551225 antibody, Gm1394 antibody, Gm1395 antibody, SSH-1 antibody, mSSH-1L antibody, SSH1L antibody, slingshot homolog 1 (Drosophila) antibody, slingshot protein phosphatase 1 antibody, Ssh1 antibody, SSH1 antibody
- Background
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Description: The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,
Aliases: SSH1,SSH1L
- Molecular Weight
- 115.5 kDa
- Gene ID
- 54434
- HGNC
- 54434
- Pathways
- CXCR4-mediated Signaling Events
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